Metabolic Syndrome and Diabetes Mellitus Case Study

metabolous Syndrome and Diabetes Mellitus - Case Study ExampleIn early diabetes mellitus, it has been stated that the ability of muscles to take up and use glucose are decreased by more than 50 percent. A major effect of glucagon occurs next in the pathology when it stimulates the write out of excessive glucose from the live. Also, it is known that blubber tissues in the bole are resistant to the effects of insulin and they arc free fatty acids which are a major contributor in the development of insulin resistant (Byrne, 2011). The release of free fatty acids from dysfunctional fat cells authorizes to increased insulin resistance. Adipocytes also release certain chemical mediator which act on the pancreatic genus Beta cells and deteriorate their function.On the other hand it is a well-known(a) fact that insulin has a lipolytic effect i.e. it causes breakdown of additional fatty tissues in the body and avoids accumulation of fat in the body. In type 2 diabetes mellitus patient s who are already obese, insulin resistance develops over time and leads to debasement of the function of beta cells of pancreas. Free fatty acids produced by adipocytes are transferred to the colored where they act on liver cells and inhibit the formation of glycogen from glucose. This results in the release of higher(prenominal) levels of glucose from the liver. Early stages of the disease see high levels of insulin and high levels of blood glucose at the same time however the with decreased functional capacity of beta cells and their destruction in the course of the disease, blood levels of insulin decrease. This decrease in the levels of insulin leads to the accumulation of fat in the body and causes abdominal obesity (Byrne, 2011).Microvascular changes are of profound importance in type 2 diabetes mellitus since they can lead to fatal consequences. One of the major causes behind these microvascular changes is continuous hypertension in type 2 diabetes. high blood pressure i s caused by loss of the ability of